A Study of Early Radiation-Induced Biological Changes As Indicators of Radiation Injury
Bethesda, MD: Federation of American Societies for Experimental Biology, Office of Medical Studies, Life Sciences Research Office, 1969. Presumed First Edition, First printing. Wraps. 214 pages. Tables. Figures. Document Control Dada R&D Form 1473. Number stamped on front cover. Number stamped and ink notation on title page. This was prepared for United States Army Medical Research and Development Command, Office of the Surgeon General, Department of the Army. This technical report is the second of three reviews of promising research opportunities to improve the treatment of radiation injury in the soldier. Part I of this report reflects the opinions of an ad hoc study group. The report has been approved by the majority, not necessarily by all, of the participants. Part II is a critical review with an annotated evaluative bibliography. The scope of this study included: the use of physical dosimetry; early clinical manifestations of radiation-induced emesis; radiation-induced cytological changes in the testes; urinary constituents as predictors of radiation injury; hematologic changes; serum iron levels as indications of hemoatopoietic dysfunction or injury; etiocholanolone in estimating bone marrow granulocyte reserves; total protein-bound neutral hexoses in the plasma as related to radiation sensitivity; effects of radiation on detoxification enzymes, drug metabolism, and biochemical changes; and chromosome aberrations as indices of radiation injury. Consideration of therapy for a number of radiation casualties impose the priorities/ Reliable biological indicators of radiation injury would significantly simplify the triage of radiation causalities and would facility diagnosis,l treatment, and prognosis of individual causalities. Condition: Good.
Keywords: Radiation Injury, Radiation-induced, Physical Dosemetry, Emesis, Cytological, Testes, Urinary, Hematologic, Serum Iron, Etiocholanolone, Bone Marrow, Granulocyte, Hexoses, Detoxification Enzymes, Biochemical Chromosome, Drug Metabolism, Exposure Vari
[Book #77070]
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