Symptomatology of Acute Radiation Effects in Humans After Exposure to doses of 75 to 4500 Rads (CGY) Free-in-Air; PSR Note 581

Los Angeles, CA: Pacific-Sierra Research Corp. 1984. Revised edition. Comb Binding. [4], 58 pages. Figures. Tables. References. Appendix A. Pathophysiology of Radiation Injury. Appendix B. Acute Sequelae of Radiation Therapy. Cover has some wear and soiling. This work was sponsored by the Defense Nuclear Agency. H. (Hubert) Rodney Withers (September 21, 1932 – February 25, 2015) was an Australian radiation biologist and physician. He made many contributions to the fields of radiobiology and clinical radiation therapy, but he is best known for his work on post-radiation tissue repair and the effects of ionizing radiation on normal tissues. Withers was born in Queensland, Australia. He received his medical degree from the University of Queensland and his Ph.D. and D.Sc. from the University of London. He worked at the Gray Laboratory in England, the National Cancer Institute, the M.D. Anderson Cancer Center, the Prince of Wales Hospital, Sydney, and at UCLA where he served as Professor and Chair of the Department of Radiation Oncology. He was a recipient of the Enrico Fermi Award, a Presidential award honoring scientists of international stature for their lifetime achievement in the development, use, or production of energy. It was established in 1956 by the United States Department of Energy in memorial of Italian-American physicist Enrico Fermi and his work in the development of nuclear power. The recipient of the award receives $100,000, a certificate signed by the President and the Secretary of Energy, and a gold medal featuring the likeness of Enrico Fermi. Robert W. Young retired from the Defense Nuclear Agency. This article distills from available data descriptions of typical human symptoms in reaction to prompt total-body ionizing radiation in the dose range 0.5 to 30 Gy midline body tissue. The symptoms are correlated with dose and time over the acute postexposure period of 6 wk. The purpose is to provide a symptomatology basis for assessing early functional impairment of individuals who may be involved in civil defense, emergency medical care and various military activities in the event of a nuclear attack. The dose range is divided into eight subranges associated with important pathophysiological events. For each subrange, signs and symptoms are designated including estimates of symptom onset, severity, duration and incidence. The purpose is to provide an empirical base for estimating combat troop performance after a nuclear weapon attack. Analyses of "composite" data, including the experience of Japanese atomic bomb survivors, was included in this analysis. Condition: Good.

Keywords: Lethal Dosage, Nuclear Accidents, Nuclear Effects, Radiation Sickness, Radiation Injury, Radiation Therapy, Radiobiology, Combat Effectiveness

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