Leukemia in Atomic Bomb Survivors; II. Observations on Early Phases of Leukemia
1954. Reprinted from Blood: The Journal of Hematology, Vol. IX, No. Y, July 1954. Wraps. Pages 663-685, [1]. Figures. Tables. References. Contains a Summary section in Spanish following the English text. The name Donald J. Kimeldorf stamped on front page. Initials RW written on front page. A total of seventy-five cases of leukemia occurring in survivors have been investigated by the Atomic Bomb Casualty Commissions and ten of these ere encountered during then course of medical and hematological surveys. Observations on some of these patients have afforded a unique opportunity to study the early hematological and preclinical phases of leukemia in atomic bomb survivors and the results of these investigations are reported in this paper. One of the summary items was that certain features of chronic myelogenous leukemia following irradiation suggested that the disorder might be due to a loss of growth-promoting or regulating factors. Blood is a peer-reviewed medical journal published by the American Society of Hematology. It was established by William Dameshek in 1946. It covers clinical and basic research in all areas of hematology, including disorders of leukocytes, both benign and malignant, erythrocytes, platelets, hemostatic mechanisms, vascular biology, immunology, and hematological oncology. Kimeldorf was a major scientific leader. His book with Ed Hunt entitled "Ionizing radiation: Neural function and behavior" is a thorough description of the physiological and behavioral effects of exposure to ionizing radiation. William Curry Moloney, MD, who studied and treated blood diseases before hematology became a medical specialty, was a professor emeritus of medicine at Harvard Medical School and former director of hematology at Brigham and Women's Hospital. He was one of the first hematologists to use chemotherapy to treat leukemia and lymphoma. Dr. Moloney was also an early contributor to the development of specific diagnostic tests, some of which are still in use today. Dr. Moloney was a recognized authority on safe procedures for blood transfusions, and his expertise in blood banks stood him in good stead in World War II, when he oversaw transfusions to wounded soldiers. After the war, in the early 1950s, Dr. Moloney directed research for the Atomic Bomb Casualty Commission in Hiroshima, Japan. Later, in the Marshall Islands, he studied the effects of errant radiation and the mechanisms that produce leukemia. Born in Minnesota on January 24, 1920, Robert Dale Lange received a BS from Macalester College at St. Paul, Minn., in 1941, and an M. D. from Washington University's School of Medicine at St. Louis, Missouri, in 1944. He was a major in the U. S. Army and served on the Atomic Bomb Casualty Commission at Hiroshima from 1951-1953. In 1964, Lange to Knoxville, Tennessee, to work for the University of Tennessee Memorial Research Center and Hospital (UTMRCH), where he rose to the rank of director. Lange became professor and chairman in the Department of Medical Biology by 1978. From 1969 to 1993 as a representative of UT, he acted as a member of their Human Subjects Committee. In 1985, Dr. Lange retired; but as a professor emeritus and practicing doctor, he continued his work in hematology. As investigator on several NASA experiments, he enabled UT's medical projects fly on the space shuttles in the late 1980s and early 1990s, including Challenger's ill-fated mission of 1986. Lange's professional career also includes over 150 journal papers and book chapters, as well as a tremendous number of reviews and abstracts. He was a Fellow of the American College of Physicians and of the International Society of Hematology and a member of many national and international societies and organizations, including Sigma XI and Pi Phi Epsilon. Condition: Good.
Keywords: Atomic Bomb Casualty Commission, Leukemia, Hiroshima, Nagasaki, Survivors, Irradiation, Chronic Myelogenous Leukemia, Medical Survey, Hematologic Survey
[Book #82445]
Price: $75.00